RP Bioseparation Columns

Triart Bio columns with organic/inorganic hybrid silica are effective for separation of biomolecules such as amino acids, peptides, proteins, antibodies, and oligonucleotides. These columns with excellent chemical durability are usable under high temperature condition which is effective for improving separation.

Silica-based and core shell columns are also available as reversed-phase columns. Metal-free columns are available for improved sensitivity and peak shape of coordinating compounds such as nucleotides or oligonucleotides.

Effective for separation of peptides, proteins ,antibodies, and oligonucleotides

Good peak shape with mobile phase suitable for LC/MS

Metal free column hardware with high pressure resistance are also available

  YMC-Triart Bio C4* YMCbasic
Modification C4
(USP L26)
equivalent to C8
(USP L7)
Particle Size [µm] 1.9, 3, 5 3, 5
Pore Size [nm / Å]
30 / 300
20 / 200
Surface Area [m2/g] - 175
pH Range 1.0 - 10.0 2.0 - 7.5
Further Information
YMC-Triart Bio C4 YMCbasic
  YMC-Triart C18* YMC-Triart Bio C18* Meteoric Core C18 BIO
Modification C18
(USP L1)
C18
(USP L1)
C18
(USP L1)
Particle Size [µm] 1.9, 3, 5 1.9, 3, 5 2.7
Pore Size
[nm / Å]
12 / 120
30 / 300
16 / 160
Surface Area [m2/g] 360 - 90
pH Range 1.0 - 12.0 1.0 - 12.0 1.5 - 10.0
Further Information
YMC-Triart C18 YMC-Triart Bio C18

The balanced hydrophobicity and silanol activity of YMC-Triart C18 make it the ideal choice for the separation of acid, neutral, basic and chelating compounds and presents itself as a true versatile stationary phase. YMC-Triart C18 can be used at pH values of 1-12, at temperatures up to 70°C and even with 100% aqueous eluents and therefore, offers the greatest flexibility for every method developer!

  YMC-Triart C18* YMC-Triart Bio C18* YMC-Triart C8* Hydrosphere C18
Modification C18
(USP L1)
C18
(USP L1)
C8
(USP L7)
C18
(USP L1)
Particle Size [µm] 1.9, 3, 5 1.9, 3, 5 1.9, 3, 5 2, 3, 5
Pore Size [nm / Å]
12 / 120
30 / 300
12 / 120
12 / 120
Surface Area [m2/g] 360 - 360 330
pH Range 1.0 - 12.0 1.0 - 12.0 1.0 - 12.0 2.0 - 8.0
Further Information
YMC-Triart C18 YMC-Triart Bio C18 YMC-Triart C8 Hydrosphere C18

*metal-free column hardware available

Title Document Type Language Phase Type Download
ADC Analysis with LC-MS compatible mobile phases Application Note E Download
Fast UHPLC analysis of commercial monoclonal antibodies at elevated temperatures using YMC-Triart Bio C4 Application Note E Download
Generic Analyses of Monoclonal Antibodies Using YMC-Triart Bio C4 Application Note E Download
High resolution analysis of oligonucleotides on RP chromatography Application Note E Download
Method development for simultaneous analysis of Amyloid β proteins using YMC-Triart Bio C4 Application Note E Download
RP Analyses of Monoclonal Antibodies with YMC-Triart Bio C4 Application Note E Download
Separation of oligonucleotides modified with disulfides using YMC-Triart Bio C4 Application Note E Download
Tipps zur Trennung von Peptiden Application Note D Download
Tips for Peptide Separation Application Note E Download
YMC Biochromatography Columns Brochure E Download
YMC Biochromatography Columns (HQ) Brochure E Download
YMC-Triart (U)HPLC Columns Brochure E Download
New wide-pore BioLC columns: YMC-Triart Bio C18 Flyer E Download
Analytical stationary phases for BioLC from YMC Overview E Download
The Principles of BioLC & YMC BioLC Phase Overview Poster E Download