K-Prep HPLC Device

K-Prep is a preparative chromatographic system corresponding from lab scale to industrial scale. Fully automatic operation by PC is possible. Chromatographic data and instrument data can be recorded automatically.

K-Prep LAB is designed for laboratory scale purification. It is applicable to columns with inner diameter of 20 to 200 mm. K-Prep FC is designed for industrial scale purification. It corresponds to a GMP production plant and is capable of corresponding to validation at IQ/OQ. K-Prep EX is an explosion-proof system for GMP production plant. Fully automatic operation by PC from non-explosion-proof area is possible.

Fully automated continuous operation via computer control.

Precise and speedy isolation by isocratic or gradient elution operation.

Economically efficient with recycle separation.

Compact

Simple maintenance.

Easy expansion.

Comply with GLP/GMP validation.

K Prep Lab

 
LAB100S
LAB100G
LAB300S
LAB300G
Gradient capability
no
yes
no
yes
Flow rate range
1-100 mL/min
1-300 mL/min
Flow rate accuracy
±2% (10 mL/min and above)
±2% (30 mL/min and above)
Maximum Pressure
15 MPa
10 MPa
High pressure line
1/16" (0.8 mmI.D.), SUS316
1/8" (2 mmI.D.), SUS316
Suction line
1/8" (2 mmI.D.), FEP
1/4" (3.9 mmI.D.), FEP
Solvent channel
2ch
4ch (2 × 2ch)
2ch
4ch (2 × 2ch)
Fraction collector
5-channel switching valve method
Sample injection
automatic injector (50 mL loop)
automatic injector (100 mL loop)
Sample syringe
25 mL (reciprocating for large quantity)
Detector
UV/VIS (195-600 nm)
Control and display
laptop PC and programmable logic controller
Software operating system
Windows 7
Power supply
AC 100V 50/60 Hz
0.6 kW
1.1 kW
0.6 kW
1.1 kW

K Prep FC

 
Gradient capability
no
yes
no
yes
Flow rate range
1-750 mL/min
1-1500 mL/min
Flow rate accuracy
±2% (75 mL/min and above)
±2% (150 mL/min and above)
Maximum Pressure
10 MPa
Fraction port
1/4", SUS316, Swagelok fitting
1/4", SUS316, Swagelok fitting
Inlet port
1/4", SUS316, Swagelok fitting
3/8", SUS316, Swagelok fitting
Solvent channel
2ch
4ch (2 × 2ch)
2ch
4ch (2 × 2ch)
Fraction collector
5-channel switching valve method
Sample injection
sample pump(1-300 mL/min)
Detector
UV/VIS (195-600 nm)
Control and display
laptop PC (changeble FA PC) and programmable logic controler
Software operating system
Windows 7
Power supply
AC 100V 50/60 Hz
0.6 kW
1.1 kW
0.6 kW
1.1 kW

K Prep EX

 
Gradient capability*
yes
yes
yes
yes
Flow rate range
30-3000 mL/min
60-6000 mL/min
125-12500 mL/min
250-25000 mL/min
Flow rate accuracy
±2%
(300 mL/min and above)
±2%
(600 mL/min and above)
±2%
(1250 mL/min and above)
±2%
(2500 mL/min and above)
Maximum Pressure
10 MPa
Fraction port
3/8", SUS316,
Swagelok fitting
1/2", SUS316,
Swagelok fitting
1/2", SUS316,
Swagelok fitting
3/4", SUS316,
Swagelok fitting
Inlet port
1/2", SUS316,
Swagelok fitting
3/4", SUS316,
Swagelok fitting
3/4", SUS316,
Swagelok fitting
1", SUS316,
Swagelok fitting
Solvent channel
4ch (2 × 2ch)
Fraction collector
5-channel switching valve method
Sample injection
sample pump
(1-300 mL/min)
sample pump
(1-1000 mL/min)
sample pump
(1-1000 mL/min)
sample pump
(30-3000 mL/min)
Detector
UV/VIS (195-600 nm)
Control and display
FA PC (control at safe area) and programmable logic controler
Software operating system
Windows 7
Power supply
three-phase AC 200V 50/60 Hz
4 kW
15 kW
15 kW
23 kW