Hydrophobic Interaction (HIC) Columns
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Hydrophobic Interaction Chromatography Column, is based on a non-porous hydrophobic polymer and is effective for separation of proteins and antibodies such as Antibody-Drug Conjugates (ADCs). It is designed and optimised for analysis and lab-scale purification of antibodies, antibody-drug conjugates and other proteins.
Optimised surface modification and column packing method realise high separation performance. High-throughput analysis with a faster flow rate can be achieved by the rigid particle and moderate backpressure.
Effective for Drug-to-Antibody Ratio (DAR) analysis of ADCs
High resolution comparable to sub-3 µm with low operating pressure
Fast analysis at high flow rates
Excellent peak shape under high loading
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BioPro HIC BF
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| Base particle | Hydrophilic polymer (polymethacrylate) |
| Particle size | 4 µm |
| Pore size | Non-porous |
| Functional group | Butyl |
| pH range | 2.0 - 12.0 |
| Temperature range | 10 - 60°C |
| Title | Document Type | Language | Phase Type | Download |
| HIC Analysis of Different Monoclonal Antibodies using Isopropanol as Modifier | Application Note | E | Download | |
| HPLC Analysis of Drug-to-Antibody with BioPro HIC BF by YMC | Application Note | E | Download | |
| YMC Biochromatography Columns | Brochure | E | Download | |
| YMC Biochromatography Columns (HQ) | Brochure | E | Download | |
| BioPro HIC BF, HT Care and Use | Care and Use Instructions | E | ||
| BioPro HIC BF by YMC | Flyer | E | Download | |
| Analytical stationary phases for BioLC from YMC | Overview | E | Download | |
| The Principles of BioLC & YMC BioLC Phase Overview | Poster | E | Download |