SFC Columns

YMC offers chiral and achiral phases for supercritical fluid chromatography (SFC) applications which provides users with a number of options for SFC separations. Alcyon SFC columns are Supercritical Fluid Chromatography (SFC) columns available with chiral/achiral stationary phases. Alcyon SFC columns are specifically packed in SFC-compatible hardware and are tested under SFC conditions.

SFC can offer some advantages over HPLC for similar applications. The low viscosity of supercritical carbon dioxide allows for analytical separations 3-5 times faster than those for normal phase HPLC. SFC is a desirable preparative chromatographic technique for purifying chemical mixtures.

Chiral and achiral stationary phases

Faster separation with high resolution

Excellent peak shape

Selectable column to suit the sample characteristics

SFC Preparative separation of Flavanone

Excellent durability

 
YMC-Triart Diol /
Alcyon SFC Triart Diol
YMC-Triart PFP /
Alcyon SFC Triart PFP
YMC-Triart C18 /
Alcyon SFC Triart C18
YMC-Triart SIL /
Alcyon SFC SIL
Base particle
organic/inorganic silica
Modification 1,2-dihydroxypropyl pentafluorophenylpropyl
C18
 unmodified
USP L20 L43 L1 -
Particle Size [µm] 1.9, 3, 5* 1.9, 3, 5* 1.9, 3, 5* 3, 5*
Pore Size [nm / Å] 12  / 120
pH Range 2.0 - 10.0 1.0 - 8.0 1.0 - 12.0 -
Pressure Limit
1.9 µm: 1,000 bar
3/5 µm: 450 bar*
5 µm: 300 bar (for YMC-Actus 20 /30 mm ID columns)
 
YMC-Pack CN / Alcyon SFC CN
YMC-Pack SIL / Alcyon SFC SIL
Base particle
silica
silica
Modification cyanopropyl unmodified
USP L10 L3
Particle Size [µm] 3, 5*
Pore Size [nm / Å] 12  / 120
pH Range 2.0 - 7.5 2.0 - 7.5
Pressure Limit
3/5 µm: 250 bar*
5 µm: 300 bar (for YMC-Actus 20 /30 mm ID columns)

* Alycon SFC columns only available in 5 µm and 300 bar max. pressure

 
CHIRAL ART Amylose-SA /
Alcyon SFC CSP
Amylose-SA
CHIRAL ART Cellulose-SB /
Alcyon SFC CSP
Cellulose-SB
CHIRAL ART Cellulose-SC /
Alcyon SFC CSP
Cellulose-SC
CHIRAL ART Cellulose-SJ /
Alcyon SFC CSP
Cellulose-SJ
Chiral Selector
Amylose
Cellulose
Cellulose
 Cellulose
 
tris (3,5-dimethylphenyl-
carbamate)
tris (3,5-dimethylphenyl-
carbamate)
tris (3,5-dichlorophenyl-
carbamate)
tris (4-methylbenzoate)
USP
L99
-
 -
-
Particle Size [µm] 3, 5
Type immobilised
pH Range 2.0 - 9.0
Pressure Limit
300 bar
(200 bar for 10 / 20 mm ID Alcyon SFC columns)
 
CHIRAL ART Amylose-C (Neo) /
Alcyon SFC CSP Amylose-C (Neo)
CHIRAL ART Cellulose-C /
Alcyon SFC CSP Cellulose-C
Chiral Selector Amylose Cellulose
 
tris (3,5-dimethylphenylcarbamate)
USP
L51
 L40
Particle Size [µm] 3, 5
Type coated
pH Range 3.5 - 6.5
Pressure Limit 300 bar
(200 bar for 10 / 20 mm ID Alycon SFC columns)

* Alycon SFC columns only available in 5 µm and 300 bar max. pressure

 
YMC-Pack
2-Ethyl pyridine*
YMC-Pack
Diethylaminopropyl*
YMC-Pack
Propyl acetamide*
YMC-Pack
Pyridine amide*
Particle Size [µm] 5 (3 and 10 on request)
Pore Size [nm / Å] 6 / 60
Shipping Solvent 2-propanol
Pressure Limit 250 bar

*not in Alcyon Hardware, but in so called "PS" type hardware also exclusively dedicated to SFC use

Title Document Type Language Phase Type Download
Rapid SFC Analysis of Vitamin D3 and Related Compounds with YMC-Triart-Diol Application Note E Download
CHIRAL ART Amylose-C, Amylose-C Neo, Cellulose-C SFC Care and Use Care and Use Instructions E Download
CHIRAL ART Amylose-SA, Cellulose-SB, Cellulose-SC SFC Care and Use Care and Use Instructions E Download
CHIRAL ART Cellulose-SJ SFC Care and Use Care and Use Instructions E Download
YMC-Triart Diol, C18, PFP + YMC-Pack SIL, CN SFC Care and Use Care and Use Instructions E Download
SFC Certificate YMC-Triart Diol Certificate E Download
SFC Compatible YMC Products Overview E Download