YMC Gel HG Series
YMC*GEL for preparative HPLC has various available functional groups, such as reversed-phase and normal-phase, and also various particle sizes from 3 µm with high-resolution to 150 µm for open column chromatography. It has achieved considerable improvements in the manufacture of its classical silica base. This has given rise to an improved generation of stationary phases with superior physical attributes.
YMC*GEL is able to work for a long period of time without particle breakage, as it uses high-density and high-strength silica gel. YMC*GEL/YMC*GEL HG packing materials are widely used both domestically and internationally.
Excellent mechanical stability (YMC*GEL HG)
Suitable for separation of peptides
Suited for large-scale purification by using dynamic axial compression column
Packing material for open column chromatography is available
| YMC*Gel ODS-A-HG |
YMC*Gel ODS-AQ-HG |
YMC*Gel C8-HG (Octyl) |
YMC*Gel C4-HG (Butyl) |
|
| Phase Code | AAG | AQG | OCG | BUG |
| Modification | C18 | C18 | C8 | C4 |
| Pore Sizes [nm / Å] | 12, 20, 30 / 120, 200, 300 |
8, 12, 20 / 80, 120, 200 |
12, 20, 30 / 120, 200, 300 |
12, 20, 30 / 120, 200, 300 |
| Surface Area [m²/g] | 330, 175, 100 | 510, 330, 175, 100 | 330, 175, 100 | 330, 175, 100 |
| Particle Sizes [µm] | 10, 15, 20, 50 | |||
| Carbon Load | 17, 12, 7% | 15, 14, 10% | 10, 7, 4% | 7, 5, 3% |
| pH Range | 2-7.5 | |||
| YMC*Gel TMS-HG (C1) |
|
| Phase Code | TMG |
| Modification | Trimethylsilane |
| Pore Sizes [nm / Å] | 12, (20, 30) / 120, (200, 300) |
| Surface Area [m²/g] | 330, (175, 100) |
| Particle Sizes [µm9 | 10, 15, 20, 50 |
| Carbon Load | 4% |
| pH Range | 2-7.5 |
| YMC*Gel CN-HG (Cyano) |
YMC*Gel Ph-HG (Phenyl) |
YMC*Gel NH2-HG (Amino) |
|
| Phase Code | CNG | PHG | NHG |
| Modification | Cyanopropyl | Phenyl | Aminopropyl |
|
Pore Sizes
[nm / Å]
|
12, (20, 30) / 120, (200, 300) |
12, (20, 30) / 120, (200, 300) |
12, (20, 30) / 120, (200, 300) |
| Surface Area [m²/g] | 330, (175, 100) | 330, (175, 100) | 330, (175, 100) |
| Particle Sizes [µm] | 10, 15, 20, 50 | 10, 15, 20, 50 | 10, 15, 20, 50 |
| Carbon Load | 7% | 9% | 3% |
| pH Range | 2-7.5 | 2-7.5 | 2-7.5 |
| YMCbasic | YMC Omega | |
| Phase Code | BA | OMG |
| Modification | C8 | proprietary |
|
Pore Sizes [nm / Å]
|
20 / 200 | proprietary |
| Surface Area [m²/g] | 175 | proprietary |
| Particle Sizes [µm] | 10, 15, 20 | 10, 20, 50 |
| Carbon Load | 7% | 15% |
| pH Range | 2-7.5 | 2-7.5 |
| Phase Code | AAG |
| Modification | C18 |
| Pore Sizes | 12, 20, 30 nm / 120, 200, 300 Å |
| Surface Area | 330, 175, 100 m2/g |
| Particle Sizes | 10, 15, 20, 50 µm |
| Carbon Load | 17, 12, 7% |
| pH Range | 2-7.5 |
YMC*Gel ODS-A-HG is YMC’s versatile octadecylsilane (ODS) C18 reversed phase packing material, suitable for a wide variety of applications. Due to its excellent performance and reproducibility it is a fully scalable C18 phase for large-scale preparative purification processes.
| Phase Code | AQG |
| Modification | C18 |
| Pore Sizes | 8; 12, 20, nm / 80; 120, 200, Å |
| Surface Area | 510; 330, 175, 100 m2/g |
| Particle Sizes | 10, 15, 20, 50 µm |
| Carbon Load | 15, 14, 10% |
| pH Range | 2-7.5 |
YMC*Gel ODS-AQ-HG is a C18 reversed phase silica-based HPLC packing material specifically designed for use in 100% aqueous eluents. As a result of the proprietary derivatisation process, YMC*Gel ODS-AQ-HG exhibits a different selectivity to that of traditional C18 stationary phases. This difference in selectivity of YMC*Gel ODS-AQ-HG can be used to advantage for HPLC separations, which are difficult to achieve with conventional C18 columns, especially for polar compounds.
| Phase Code | OCG |
| Modification | C8 |
| Pore Sizes | 12, 20, 30 nm / 120, 200, 300 Å |
| Surface Area | 330, 175, 100 m2/g |
| Particle Sizes | 10, 15, 20, 50 µm |
| Carbon Load | 10, 7, 4% |
| pH Range | 2-7.5 |
YMC*Gel C8-HG is one of YMC’s most versatile bonded phases and an excellent alternative to C18 selectivities. Due to its moderate hydrophobicity, YMC*Gel C8-HG is well suited for the separation of hydrophobic compounds which are too strongly retained on C18 phases or for samples that require greater retention than that provided by C4 packings. Compared to C18 phases, retention times of non-polar compounds will be lower on C8 material due to the reduced carbon load.
| Phase Code | BUG |
| Modification | C4 |
| Pore Sizes | 12, 20, 30 nm / 120, 200, 300 Å |
| Surface Area | 330, 175, 100 m2/g |
| Particle Sizes | 10, 15, 20, 50 µm |
| Carbon Load | 7, 5, 3% |
| pH Range | 2-7.5 |
Due to shorter alkyl chains YMC*Gel C4-HG has a lower hydrophobicity than both C18 and C8 phases. As a result retention times for non-polar samples tend to be shorter on YMC*Gel C4-HG, making it an ideal choice for faster separations.
| Phase Code | TMG |
| Modification | Trimethylsilane |
| Pore Sizes | 12, (20, 30) nm / 120, (200, 300) Å |
| Surface Area | 330, (175, 100) m2/g |
| Particle Sizes | 10, 15, 20, 50 µm |
| Carbon Load | 4% |
| pH Range | 2-7.5 |
YMC*Gel TMS-HG shows the lowest retention due to hydrophobic interaction of all reversed phase packing materials. It is useful for fast separations of highly hydrophobic samples that exhibit strong retention characteristics and are difficult or impossible to separate on conventional reversed phase packings. In addition, YMC*Gel TMS-HG can sometimes achieve greater retention and better separations of hydrophilic compounds than other reversed phase columns.
A narrower particle size distribution with lower tendency for the HG-silica material to produce fines translates directly into a reduced backpressure of preparative processes. On average a 7% backpressure reduction can be seen, which increases dramatically with each repacking step.
YMC*Gel is available in a variety of different pore sizes. Pore sizes are usually matched to sample molecule sizes. Pore sizes can also be used to adjust ligand density and hence retention characteristics of a bonded phase, since the size of the pores also affects the total media surface area in a packed column.
The basis for every successful separation is the selection of the appropriate stationary phase. YMC offers one of the world‘s largest portfolios of selectivities, designed to handle even the most demanding separations.
