YMC HILIC Columns
HILIC HPLC/UHPLC columns from YMC are rugged stationary phases which provide improved LC/ESI-MS response, direct SPE solvent compatibility and complementary selectivity to reversed phases. This is important to R&D and drug metabolism scientists since the impurity or metabolite is frequently more polar and present at much lower concentrations than the parent compound.
With YMC HILIC columns, these very polar compounds elute later than the higher hydrophobic parent compound, thereby minimizing the MS ion suppression that can occur at the beginning of the chromatogram.
YMC HILIC provides an ideal mechanism for the analysis of extremely polar analytes
YMC offers a wide variety of HILIC phases to cover a broad range of polar selectivities
HILIC eluents are compatible with LC-MS systems
| YMC-Triart Diol-HILIC | YMC-Pack SIL | YMC-Pack PVA-Sil | YMC-Pack CN | |
| Modification | 1,2-Dihydroxypropyl (USP L20) |
Silica (USP L3) |
Polyvinyl alcohol (USP L24) |
Cyanopropyl (USP L10) |
| Particle Size [µm] | 1.9, 3, 5 | 3, 5 | 5 | 3, 5 |
|
Pore Size
[nm / Å]
|
12 / 120
|
6, 12, 20, 30/
60, 120, 200, 300
|
12 / 120
|
12, 30 /
120, 300
|
| Surface area [m2/g] | 360 | 450, 330, 175, 100 | 330 | 330, 175 |
| pH Range | 2.0 - 10.0 | 2.0 - 7.5 | 2.0 - 9.5 | 2.0 - 7.5 |
| YMC-Pack Diol-NP | YMC-Pack Polyamine II | YMC-Pack NH2 | YMC-Pack TMS | |
| Modification |
1,2-Dihydroxypropyl
(USP L20)
|
Sec./ tert. Amines
(USP L111)
|
Aminopropylsilane (USP L8) |
Trimethylsilane (USP L13) |
| Particle Size [µm] | 5 | 5 | 3, 5 | 3, 5 |
|
Pore Size
[nm / Å]
|
6, 12 /
60, 120
|
12 / 120
|
12 / 120 |
12, 30 /
120, 300
|
| Surface area [m2/g] | 450, 330 | 330 | 330 | 330, 175 |
| pH Range | 2.0 - 7.5 | 2.0 - 7.5 | 2.0 - 7.5 | 2.0 - 7.5 |
| Title | Document Type | Language | Phase Type | Download |
| YMC-Pack Diol NP, PVA-Sil Care and Use | Care and Use Instructions | E | Download | |
| YMC-Pack Polyamine II and NH2 Care and Use | Care and Use Instructions | E | Download | |
| YMC-Pack Silica Care and Use | Care and Use Instructions | E | Download | |
| YMC-Triart Diol-HILIC Care and Use | Care and Use Instructions | E | Download | |
| Analytical stationary phases for HPLC and UHPLC from YMC | Overview | E | Download | |
| YMC Classic Columns | eCatalogue | E | Download | |
| YMC Normal Phase Classics - YMC Classic Columns | eCatalogue Chapter | E | Download |