YMC-Pack ODS

YMC’s best-selling, world-renowned YMC-Pack ODS-series is widely known for its variety of phase, such as reversed-phase packing materials including ODS, normal-phase packing materials and size exclusion packing materials. It has a variety of selectivities for nonpolar, moderately polar and polar compounds. Further, YMC-Pack ODS-AQ was the first so called “AQ-column”, which can be used under 100% aqueous conditions!

YMC-Pack ODS columns are successfully used for the validation of analytical HPLC methods and for long term reproducible preparative HPLC processes.

Excellent resolution

Reproducibility

Can be used under aqueous conditions

  YMC-Pack ODS-AQ YMC-Pack ODS-A YMC-Pack ODS-AM YMC-Pack ODS-AL
Modification C18 (USP L1)
Particle Size [µm] 3, 5 3, 5 3, 5 5
Pore Size [nm / Å] 12, 20 / 120, 200 12, 20, 30 / 120, 200, 300* 12 / 120 12 / 120
Surface Area {m2/g] 330, 175  330, 175, 100 330 330
Endcapping yes yes yes no
Carbon Load 14, 10% 17, 12, 7% 17% 17%
pH Range 2.0 - 7.5

*not all combinations of particle and pore size are available

Particle Size 3 µm, 5 µm 
Pore Size 12, 20 nm / 120, 200 Å
Surface Area 330, 175 m2/g
Endcapping yes
Carbon Load 14, 10%
pH Range 2-7.5

YMC-Pack ODS-AQ is a “hydrophilic” C18 material with a balanced surface chemistry leading to elution of moderately basic compounds with little or no peak tailing and strong retention of polar sample solutes.
YMC-Pack ODS-AQ is able to resolve compounds with minor differences in polarity from closely related substances. As a result, YMC-Pack ODS-AQ is an excellent tool for separating drugs and corresponding metabolites, pesticides and degradation products, or peptides and protein digests etc.

Particle Size 3 µm, 5 µm 
Pore Size 12, 20, 30 nm / 120, 200, 300 Å
Surface Area 330, 175,100  m2/g
Endcapping yes
Carbon Load 17,12, 7%
pH Range 2-7.5

YMC-Pack ODS-A, YMC’s classic reversed phase column, is renowned worldwide because of its unique performance and reproducibility. The classic “workhorse” phase YMC-Pack ODS-A is a fully endcapped material.
YMC-Pack ODS-A is frequently used for polar to moderately nonpolar substances in pharmaceutical, biochemical and environmental applications as well as for separations in the field of food technology.

Particle Size 3 µm, 5 µm 
Pore Size 12 nm / 120 Å
Surface Area 330 m2/g
Endcapping yes
Carbon Load 17%
pH Range 2-7.5

YMC-Pack ODS-AM is a high quality analytical C18 material, with a very tight specification. Due to the guaranteed long term reproducibility, YMC-Pack ODS-AM columns are the ideal choice for establishing validated HPLC analysis.
YMC-Pack ODS-AM has appropriate selectivity for polar to moderately nonpolar pharmaceuticals, organic intermediates, biological and natural products found in the chemical and pharmaceutical industry.

Particle Size 5 µm 
Pore Size 12 nm / 120 Å
Surface Area 330 m2/g
Endcapping no
Carbon Load 17%
pH Range 2-7.5

YMC-Pack ODS-AL uses not only hydrophobic interaction but also secondary interactions with reactive residual silanol groups on the silica surface to affect separation. This results in a different selectivity from conventional ODS columns. YMC-Pack ODS-AL is the ideal choice for mixed mode separations.
Due to the residual silanol groups YMC-Pack ODS-AL shows relatively greater retention of pyridines for example.

Title Document Type Language Phase Type Download
YMC microLC Brochure E Download
YMC-Pack RP & NP Columns Care and Use Care and Use Instructions E Download
MSDS Silica based NP/RP Bulk MSDS E Download
Analytical stationary phases for HPLC and UHPLC from YMC Overview E Download
YMC Classic Columns eCatalogue E Download
YMC Reversed Phase Classics - YMC Classic Columns eCatalogue Chapter E Download