YMC Triart

YMC-Triart Series are organic/inorganic hybrid silica based columns that emphasize versatility. The main features are superior durability, good peak shape for all kinds of compounds, and reproducibility. With the same selectivity across different particle sizes, smooth method transfer between UHPLC and HPLC can be performed.

Moreover, alternative bonded phases such as C8 and HILIC supplement the performance of C18, allowing separations that C18 cannot achieve. For separation of proteins including antibodies, YMC-Triart Bio C4 with wide pore is effective.

YMC-Triart Prep, preparative packing materials with great chemical stability are also available

Great chemical durability in an expanded pH range provided by hybrid particles

Great peak shapes without adsorption/peak tailing

Identical selectivity and excellent peak shapes across various particle sizes

Comparison of separation selectivity among YMC-Triart columns

 
C18
C18 ExRS
Bio C18
C8
Bio C4
Phenyl
PFP
Diol-HILIC
Base
organic / inorganic silca
Stationary Phase
(USP class)
C18
(L1)
C18
(L1)
C18
(L1)
C8
(L7)
C4
(L26)
Phenylbutyl
(L11)
Pentafluoro-phenylpropyl
(L43)
1,2-Dihydroxypropyl
(L20)
Particle Size [µm] 1.9, 3, 5
Pore Size
[nm / Å]
12 / 120 8 / 80 30 / 300 12 / 120 30 / 300 12 / 120 12 / 120 12 / 120
Bonding Type trifunctional
Endcapping
multi-
stage
multi-
stage
multi-
stage
multi-
stage
multi-
stage
multi-
stage
none none
Carbon Load 20% 25% - 17% - 17% 15% -
Surface Area [m²/g] 360 430 - 360 - 360 360 360
pH Range 1.0 - 12.0 1.0 - 12.0 1.0 - 12.0 1.0 - 12.0 1.0 - 10.0 1.0 - 10.0 1.0 - 8.0 2.0 - 10.0
Max. Temperature
[pH 1-7 / pH 7-12]
90°C /
50°C
90°C /
50°C
90°C /
50°C
90°C /
50°C
90°C /
50°C
50°C 50°C 50°C
100% Aqueous Eluents
yes
-
yes
-
yes
yes yes yes
Hardware
  • stainless steel
  • metal-free (for bioseparations and coodinating compounds)
  • capillary (for nano/microLC)
Modification C18 (USP L1)
Particle Sizes 1.9 µm, 3 µm, 5 µm
Pore Size 8 nm / 80 Å
Surface Area 430 m²/g
Carbon Load 25%
pH Range 1-12
Max. Temperature pH 1-7: 90°C
pH 7-12: 50°C

The balanced hydrophobicity and silanol activity of YMC-Triart C18 make it the ideal choice for the separation of acid, neutral, basic and chelating compounds and presents itself as a true versatile stationary phase. YMC-Triart C18 can be used at pH values of 1-12, at temperatures up to 70°C and even with 100% aqueous eluents and therefore, offers the greatest flexibility for every method developer!

Modification C18 (USP L1)
Particle Sizes 1.9 µm, 3 µm, 5 µm
Pore Size 8 nm / 80 Å
Surface Area 430 m²/g
Carbon Load 25%
pH Range 1-12
Max. Temperature pH 1-7: 90°C
pH 7-12: 50°C

YMC-Triart C18 ExRS is the only YMC phase with 25% carbon load! Ultra-high carbon load represents the key for the separation of extremely non-polar substances and closely related substances, such as positional or steric isomer. Analyse of even extremely hydrophobic substances by HPLC or UHPLC is possible.

Modification C18 (USP L1)
Particle Sizes 1.9 µm, 3 µm, 5 µm
Pore Size 30 nm / 300 Å
Surface Area -
Carbon Load -
pH Range 1-12
Max. Temperature pH 1-7: 90°C
pH 7-12: 50°C

Similar to YMC-Triart Bio C4, YMC-Triart Bio C18 offers 300 Å pore size and is specifically designed with proteins, peptides, and oligonucleotides in mind. The hybrid-silica base and polymeric bonding provide a rugged C18 phase with a wide pH range (1-12) that excels at separating mid-MW biomolecules (10k Da to 100k Da). YMC- Triart Bio C18 is available in 1.9 µm particle size for UHPLC as well as 3 and 5 µm for standard HPLC.

Modification C8 (USP L7)
Particle Sizes 1.9 µm, 3 µm, 5 µm
Pore Size 12 nm / 120 Å
Surface Area 360 m²/g
Carbon Load 17%
pH Range 1-12
Max. Temperature pH 1-7: 90°C
pH 7-12: 50°C

The versatility of YMC-Triart C8 makes it an optimum alternative for analysing acidic, neutral, basic and chelating compounds or metabolites. YMC-Triart C8 provides a less hydrophobic stationary phase offering a different selectivity and reduced retention times compared to YMC-Triart C18.

Modification C4 (USP L26)
Particle Sizes 1.9 µm, 3 µm, 5 µm
Pore Size 30 nm / 300 Å
Surface Area -
Carbon Load -
pH Range 1-10
Max. Temperature pH 1-7: 90°C
pH 7-12: 50°C

YMC-Triart Bio C4 is a new wide-pore phase for UHPLC and HPLC. Due to its 300 Å pore size, it is designed for peptide and protein separations. As usual excellent YMC reproducibility is provided. High pH and temperature stability is guaranteed. pH values from 1 to 10 as well as temperatures up to 90°C can be used!

Modification Phenyl butyl (USP L11)
Particle Sizes 1.9 µm, 3 µm, 5 µm
Pore Size 12 nm / 120 Å
Surface Area 360 m²/g
Carbon Load 17%
pH Range 1-10
Max. Temperature 50°C

Separation of aromatic compounds is ideally been done by YMC-Triart Phenyl. Due to π-π-interactions YMC-Triart Phenyl offers a unique selectivity at highest phase stability.

Modification Pentafluorophenyl propyl (USP L43)
Particle Sizes 1.9 µm, 3 µm, 5 µm
Pore Size 12 nm / 120 Å
Surface Area 360 m²/g
Endcapping none
Carbon Load 15%
pH Range 1-8
Max. Temperature 50°C

With YMC-Triart PFP additional separation mechanisms are involved. The interaction of the analytes with the stationary phase is possible via hydrogen-bonding and/or dipole-dipole, aromatic or hydrophobic interactions. YMC-Triart PFP is best suited to chromatography of compounds with polar groups such as halogens. It offers high stereo selectivity and excellent (geometric) isomer separation.

Modification 1,2-Dihydroxypropane (USP L20)
Particle Sizes 1.9 µm, 3 µm, 5 µm
Pore Size 12 nm
Surface Area 360 m²/g
Endcapping none
pH Range 2-10
Max. Temperature 50°C

YMC-Triart Diol-HILIC is ideal for a separation of polar and hydrophilic compounds which are not retained by reversed phase (C18, C8, and others) chromatography. Excellent reproducibility, even at high pH and temperature, is achieved by the use of dihydroxypropyl groups – these are neutral functional groups exhibiting low nonspecific adsorption.

Title Document Type Language Phase Type Download
7 Tetrahydrocannabinol (THC) Related Compounds with YMC-Triart C18 Application Note E Download
Baseline separation of chlorophenols as a result of outstanding steric selectivity of YMC-Triart C18 ExRS Application Note E Download
Easy and quick HPLC analysis of Aflatoxin in milk with YMC-Triart C18 Application Note E Download
Fast and Easy Achiral and Chiral Analysis of Cannabinoids Using YMC-Triart C18, Meteoric Core C18 and CHIRAL ART Amylose-C Application Note E Download
Fatty acid isomers with YMC-Triart C18 ExRS without derivatisation Application Note E Download
High resolution analysis of oligonucleotides on RP chromatography Application Note E Download
LC-MS/MS Analysis of Sphingophospholipids Using YMC-Triart Metal-free Column Application Note E Download
MicroLC detection of gluten in flour and cookies with YMC-Triart C18 Application Note E Download
MicroLC detection of veterinary drug residues in food with YMC-Triart C18 Application Note E Download
Rapid SFC Analysis of Vitamin D3 and Related Compounds with YMC-Triart-Diol Application Note E Download
Separation of Native and Unsaturated Fatty Acids with YMC-Triart C18 ExRS Application Note E Download
Separation of structural analogues Vitamin D with YMC-Triart C18 ExRS Application Note E Download
Simultaneous LC/MS/MS Analytics of Fumonisins (B1, B2, B3) Application Note E Download
Steric recognition enables separation of methyl linolenate with YMC-Triart C18 ExRS Application Note E Download
Steroids on YMC-Triart Phenyl - Excellent alternative to ODS phases Application Note E Download
UHPLC Analysis of benzodiazepines and their metabolites by LC-MS/MS Application Note E Download
Vitamin D Level Determination in Serum with YMC-Triart C18 ExRS Application Note E Download
Vitamin D2 and D3 separation by new highly hydrophobic UHPLC HPLC YMC_Triart C18 ExRS Application Note E Download
YMC Application Collection Pesticides: Achiral and Chiral Applications Application Note E Download
YMC-Triart C18: Amino acids with 100% aqueous mobile phase Application Note E Download
YMC-Triart (U)HPLC Columns Brochure E Download
Instructions for Column Connection YMC-Triart Metal-Free Columns Care and Use Instructions E Download
YMC-Triart C18, C18 ExRS, C8, Bio C4, Phenyl, PFP Care and Use Care and Use Instructions E Download
YMC-Triart Diol-HILIC Care and Use Care and Use Instructions E Download
YMC-Triart Metal-Free Columns Instructions for Column Connection Care and Use Instructions E Download
Improving Your LC/MS Results by Using Metal-free Hardware! Flyer E Download
MSDS YMC-Triart Bulk MSDS E Download
Analytical stationary phases for HPLC and UHPLC from YMC Overview E Download
Easy YMC-Triart Column Selection for Method Development (Radar Chart) Poster E Download
Reversed-Phase Method Development Strategy Poster E Download